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Finasteride (marketed as Proscar, Propecia, Fincar, Finpecia, Finax, Finast, Finara, Finalo, Prosteride, Gefina, Appecia, Finasterid IVAX, Finasterid Alternova) is a synthetic antiandrogen which acts by inhibiting type II 5-alpha reductase, the enzyme that converts testosterone to dihydrotestosterone (DHT). It is used as a treatment in benign prostatic hyperplasia (BPH) in low doses, and prostate cancer in higher doses. A May, 2008 study indicates that Finasteride reduces the rate of prostate cancer by 30% (see below). It is also indicated for use in combination with doxazosin therapy to reduce the risk for symptomatic progression of BPH. Additionally, it is registered in many countries for androgenetic alopecia (male-pattern baldness). Finasteride was approved initially in 1992 as Proscar, a treatment for prostate enlargement, but the sponsor had studied 1 mg of finasteride and demonstrated hair growth in male pattern hair loss. On December 22, 1997, the USFDA approved finasteride to treat male pattern hair loss.
Special warnings about Propecia If there's even a possibility that they're pregnant, women should avoid handling a crushed or broken Propecia tablet for fear of absorbing some of the active ingredient through the skin. Whole tablets are safe to handle thanks to a protective outer coating. Use Propecia with caution if you have liver problems. Propecia lowers readings of the PSA screening test for prostate cancer. If you're scheduled to have your PSA level checked, make sure the doctor knows you're taking Propecia. Possible food and drug interactions when taking Propecia No significant drug interactions have been reported. Special information if you are pregnant or breastfeeding Avoid even touching the active ingredient in Propecia if there's a chance that you're pregnant. Recommended dosage ADULT MEN The recommended dosage, for men only, is 1 tablet daily. Overdosage Although no specific information is available on Propecia overdose, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately. Propecia (Finasteride) dosage
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